Hemophilia heem-o-FILL-ee-ah is a rare bleeding disorder in which the blood doesn't clot normally. If you have hemophilia, you may bleed for a longer time than others after an injury.
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Sickle cell disease is an inherited blood disorder. It is marked by flawed hemoglobin. So, sickle cell disease interferes with the delivery of oxygen to the tissues. They can move through the blood vessels easily. Cells with sickle cell hemoglobin are stiff and sticky.
This can block small blood vessels and the movement of healthy, normal oxygen-carrying blood. The blockage can cause pain.
But, sickle cells only live for about 10 to 20 days. Also, sickle cells may be destroyed by the spleen because of their shape and stiffness. The spleen helps filter the blood of infections. Sickled cells get stuck in this filter and die.
The sickled cells also damage the spleen. This puts you are at greater at risk for infections. What causes sickle cell disease? Sickle cell is an inherited disease caused by a defect in a gene.
A person will be born with sickle cell disease only if two genes are inherited—one from the mother and one from the father. A person who inherits just one gene is healthy and said to be a "carrier" of the disease. A carrier has an increased chance of having a child with sickle cell disease if he or she has a child with another carrier.
What are the risk factors for sickle cell disease? Having a family history of sickle cell disease increases your risk for the disease. In the United States, it mainly affects African Americans.
What are the symptoms of sickle cell disease? The following is a list of symptoms and complications associated with sickle cell disease. However, each person may experience symptoms differently.Sickle cell disease can cause pain episodes, damage to vital organs like the lungs and kidneys, and even death.
Young children with sickle cell disease are especially prone to certain dangerous bacterial infections, like pneumonia (inflammation of the lungs) and meningitis (inflammation of the brain and spinal cord).
Jul 06, · In some cases, a weakened blood vessel may burst, spilling blood into the brain (hemorrhage) that can cause stroke and brain damage.
Other neurological problems include headache, weakness, seizures, pain, and problems with speech, vision, or movement.
Sickle cell anemia (sickle cell disease) is a disorder of the blood caused by an inherited abnormal hemoglobin (the oxygen-carrying protein within the red blood cells). The abnormal hemoglobin causes distorted (sickled appearing under a microscope) red blood cells.
In people with sickle cell disease, abnormal hemoglobin molecules - hemoglobin S - stick to one another and form long, rod-like structures. These structures cause red blood cells to become stiff, assuming a sickle shape. Their shape causes these red blood cells to pile up, causing blockages and damaging vital organs and tissue.
Blocked blood flow can cause pain, serious infections, and organ damage. Life expectancy in people who have this disease is shortened. Anemia is a condition in which your blood has a lower than normal number of red blood cells. Diagnosis Diagnostic testing for AL amyloidosis involves blood tests, urine tests and biopsies.
Blood and/or urine tests can indicate signs of the amyloid protein, but only bone marrow tests or other small biopsy samples of tissue or organs can positively confirm the diagnosis of amyloidosis.